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\nRole Summary:\n\nThis role plays a critical role in advancing our pipeline of novel treatments through the application of cutting-edge bioanalytical techniques. This includes designing, developing, optimizing, and validating bioanalytical in complex biological matrices with a focus on muscle tissue and fluids. The person in this role is expected to utilize state-of-the-art LC-MS/MS instrumentation for the quantitative analysis of biomarkers, metabolites, and therapeutic compounds in preclinical and clinical samples.\n\nThis role is based in Waltham, MA without the possibility of being a remote role. Candidates must be able to relocate.\n\nPrimary Responsibilities Include:\n\n\n* Provide bioanalytical support for portfolio, including complex method development and troubleshooting for PK and immunogenicity assays across several programs.\n\n* Collaborate cross-functionally with Platform, Research and Non-Clinical teams.\n\n* Design, develop and/or optimize sensitive quantitative assays to measure Dyne proprietary drugs in different matrices (plasma, urine, tissues) and from different species (rodents, non-human primates, human).\n\n* Setup and maintain lab instrumentation.\n\n* Evaluate assay performance, ability to troubleshoot issues.\n\n* Perform data analysis and interpretation.\n\n* Track progress against project timelines, generate regular status updates, and communicate progress and issues to management.\n\n* Maintain a well-documented laboratory notebook.\n\n* Effectively manage workload with minimal supervision.\n\n* Adhere to safe laboratory practices.\n\n* Multi-task across several projects and manage time effectively to achieve results.\n\n* Collaborate to identify external vendors (CRO) for new outsourced projects and request contracts.\n\n* Transfer bioanalytical assays to CROs, oversee assay validation and sample testing. \n\n\n\n\nEducation and Skills Requirements:\n\n\n* BS or MS in Pharmaceutical sciences with at least 6-8 years of experience in the pharmaceutical industry or PhD degree with at least 4 years of industry experience\n\n* Broad, and in-depth knowledge of FDA bioanalytical guidance to industry\n\n* Hands-on assay development experience with different ligand binging assay formats and detection methods required\n\n* Strong assay troubleshooting, data analysis and interpretation skills\n\n* Excellent verbal and written communication skills\n\n* Ability to work collaboratively in a team-oriented environment\n\n* Strong attention to detail, organizational skills, and ability to multitask\n\n* Demonstrated ability to troubleshoot and solve problems\n\n\n\n\n \n\n#LI-Onsite \n\n#Salary and compensation\n
No salary data published by company so we estimated salary based on similar jobs related to Senior and Senior jobs that are similar:\n\n
$60,000 — $110,000/year\n
\n\n#Benefits\n
💰 401(k)\n\n🌎 Distributed team\n\n⏰ Async\n\n🤓 Vision insurance\n\n🦷 Dental insurance\n\n🚑 Medical insurance\n\n🏖 Unlimited vacation\n\n🏖 Paid time off\n\n📆 4 day workweek\n\n💰 401k matching\n\n🏔 Company retreats\n\n🏬 Coworking budget\n\n📚 Learning budget\n\n💪 Free gym membership\n\n🧘 Mental wellness budget\n\n🖥 Home office budget\n\n🥧 Pay in crypto\n\n🥸 Pseudonymous\n\n💰 Profit sharing\n\n💰 Equity compensation\n\n⬜️ No whiteboard interview\n\n👀 No monitoring system\n\n🚫 No politics at work\n\n🎅 We hire old (and young)\n\n
\n\n#Location\nWaltham, Massachusetts, United States
# How do you apply?\n\nThis job post has been closed by the poster, which means they probably have enough applicants now. Please do not apply.
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