\nRoivant’s mission is to systematically reduce the time, cost, and risk of delivering new medicines to market by accelerating the development of promising drug candidates to improve the lives of patients ad their families. Since its inception in 2014, Roivant has achieved the following critical milestones in support of its vision: built over 20 portfolio companies (Vants); 5 successful IPOs; 10 consecutive positive phase 3 trials; 6 FDA approvals; >10$B in global pharma partnerships and proceeds; expanding pipeline of assets across various modalities and therapeutic areas; successful commercial launch of VTAMA®, (tapinarof) cream, 1%, for the topical treatment of plaque psoriasis in adults.  Building upon this track record of establishing a robust pipeline through in-licensing and acquisition of novel assets and technology platforms, Roivant is currently building new capabilities in drug discovery and expanding upon existing development disciplines to become the leading tech-enabled pharmaceutical company.\n\nAs the centralized engine for innovation and development the Roivant R&D team is responsible for: 1) working hand in hand with Business Development to establish the scientific rationale and creating/underwriting a development strategy for in-licensing opportunities, with a focus on oncology, immunology and rare diseases; 2) providing tactical and strategic R&D support to stand up new portfolio companies (Vants) and advance development efforts across the portfolio.  \n\nTo learn more about our story and company culture, please visit us at https://roivant.com/\n\nPosition Summary:\n\nThe Vice President of Clinical Operations will play a key role in advancing the clinical development of programs across the Roivant portfolio and supporting the launch of newly created biotech subsidiaries (Vants) across a diverse range of therapeutic areas. This person, together with the Clinical Operations team, will establish and execute innovative and expedient program/trial execution strategies and priorities in alignment with company goals and in collaboration with the cross functional teams within and outside R&D.  This individual must be highly self-motivated, optimization-minded, and collaborative amongst internal stakeholders as well as external and CRO partners as appropriate, with a deep sense of personal ownership of deliverables. They will also need to have excellent communication skills across diverse audiences, including executive leadership within Roivant and vants, technical, business, and operational groups, and with contract research organizations and vendors. They need to enroll trials expeditiously across disease areas with high data quality through their own work and that of their team.\n\nKey Responsibilities:\n\n\n* Leadership responsibility for Clinical Operations strategy, initiation and execution of clinical trials across all phases, including (but not limited to) CRO/vendor selection, site engagement, contracts & budgets, CRO oversight, and proactive risk management to ensure the quality conduct of trials with a high level of data integrity\n\n* Provide excellent direct line management and training/mentoring of Clinical Operations team members, creating a nimble, versatile, world-class, high performing operations team\n\n* Scoping geographic region and site specific approaches with substantial experience in global clinical trial execution for successful incubation of trials during diligence and launch post transaction is highly critical\n\n* Demonstrate leadership in preemptively identify and develop outlines of indication- and phase-specific operations plan before and during diligence to arrive at the most realistic estimates of enrolment and data availability timelines in the integrated development plan underwritten in the Investment Thesis\n\n* Work cross functionally to drive the strategy and own implementation for clinical programs and manage the integrated development plans to deliver against company goals\n\n* Lead and supervise all aspects of study progress from concept to close-out to assure adherence to Good Clinical Practice, intended timelines and achievement of study goals while ensuring quality in accordance with regulatory guidelines; \n\n* Serve as Clinical Operations point of contact for strategic governance bodies (e.g., Safety Team, Project Team), as well as portfolio planning and business development opportunities\n\n* Lead Clinical Study teams in gathering and reporting key study data collection and presentation to use in support of regulatory filings, as well as project team and management communications\n\n* Oversee identification, qualification and selection of CROs and vendors needed to conduct clinical trials including approval of Master Services Agreements and Task Orders with CRO\n\n* Establish governance procedures for CROs and key clinical vendors ensuring continuous performance oversight and process improvement \n\n* Liaise with KOLs, Investigators, and clinical site staff to ensure optimal Sponsor-Site relationships\n\n* Liaise effectively with vant staff, including management and execution team\n\n* Provide scientific/clinical expertise in the design and interpretation of clinical studies\n\n* Build and implement repeatable and scalable approaches to enrollment projections, geostrategy and patient enrollment essential for future vant planning and execution   \n\n* Implement novel technologies, platforms, tools to improve and scale core capabilities such as enrollment projections, geostrategy and patient enrollment essential for future vant planning and execution  \n\n* Ensure effective project or program communications and updates to internal and external stakeholders through meetings, presentations, and other methods\n\n\n\n\nRequirements:\n\n\n* Bachelor's Degree in a scientific discipline; advanced degree preferred\n\n* 15+ years of clinical operations management experience, including trial leadership experience\n\n* Experience managing CROs and key clinical vendors required\n\n* Experience developing clinical study protocols in conjunction with a study team required\n\n* Track record leading clinical operations teams to deliver on time execution and results, including outsourced support\n\n* Early and late phase investigational product development experience required \n\n* Demonstrated ability to set and prioritize goals and objectives; excellent time management, negotiation, problem-solving and organizational skills\n\n* Proven excellence in clinical operations strategy including simultaneous oversight of multiple trials, and ideally experience managing multiple vendors in dispersed project team environments\n\n* Experience in building infrastructure (including SOPs) required\n\n* Ability to work independently and collaboratively in a fast-paced, matrixed team environment consisting of internal and external team members\n\n* Entrepreneurial mindset, bringing in creative ideas to challenge the status quo of clinical trial execution\n\n* Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines\n\n* Excellent understanding and demonstrated application of FDA guidelines, Good Clinical Practices and applicable Standard Operating Procedures\n\n* Strong leadership skills with ability to innovate and collaborate with a small team to articulate clear clinical strategy\n\n* Strong communication and presentation skills\n\n\n\n\nRoivant Sciences provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.\n\nWe will not accept unsolicited resumes nor outreach from agencies. Please do not send agency resumes to our website or Roivant Sciences and affiliated employees. Thanks! \n\n#Salary and compensation\n No salary data published by company so we estimated salary based on similar jobs related to Design and Design jobs that are similar:\n\n $30,000 — $50,000/year\n
\n\n#Benefits\n 💰 401(k)\n\n🌎 Distributed team\n\n⏰ Async\n\n🤓 Vision insurance\n\n🦷 Dental insurance\n\n🚑 Medical insurance\n\n🏖 Unlimited vacation\n\n🏖 Paid time off\n\n📆 4 day workweek\n\n💰 401k matching\n\n🏔 Company retreats\n\n🏬 Coworking budget\n\n📚 Learning budget\n\n💪 Free gym membership\n\n🧘 Mental wellness budget\n\n🖥 Home office budget\n\n🥧 Pay in crypto\n\n🥸 Pseudonymous\n\n💰 Profit sharing\n\n💰 Equity compensation\n\n⬜️ No whiteboard interview\n\n👀 No monitoring system\n\n🚫 No politics at work\n\n🎅 We hire old (and young)\n\n
\n\n#Location\nNew York City, New York, United States

\nAlpine Immune Sciences is a leading clinical-stage biopharmaceutical company dedicated to discovering and developing innovative, protein-based immunotherapies for autoimmune and inflammatory diseases. Exciting challenges lie ahead—guided by our core values, we’ll meet these challenges. Join us!\n\n\n\n\nThe Senior Director, Regulatory Affairs is a leader, who provides vision and direction in a fast-paced, dynamic, and competitive drug development environment. They report to the Executive Director of Regulatory Affairs and are responsible for contributing to the global company regulatory strategy and working closely with cross functional leaders in all regulatory interactions and activities for the development of Alpine’s therapeutic candidates. \n \nDuties and responsibilities:\n \n•Lead strategic regulatory activities to support cross functional product development teams in alignment with corporate and program goals.\n•Serve as the global regulatory lead for select development programs.\n•Develop and implement regulatory strategy for INDs, CTAs, BLAs; MAAs, NDAs; identify opportunities globally for expedited development. \n•Provide strategic regulatory input on clinical, including therapeutic indication(s), study designs, patient populations, pediatric development; CMC; and nonclinical development. \n•Prepare and coordinate authoring, review, and submission of high-quality regulatory documents, including Information Requests, IND/CTA submissions, BLAs/MAAs/NDA, Annual Reports/DSURs, briefing books for health authority interactions, clinical documents to ensure they are complete, well-written, and meet all relevant regulatory requirements. This may involve writing relevant sections of documents.\n•Lead regulatory aspects of clinical study executing including management of correspondence with health authorities and coordination with partner companies and vendors.\n•Ensure compliance of all Alpine activities with applicable global regulations, standards, and clinical practice guidelines. \n•Monitor regulatory developments within the industry globally, evaluate impact to Alpine’s programs, and provide actionable guidance to internal and external partners to adapt to and address the developments. \n•Identify and communicate with senior management and cross-functional teams regarding potential regulatory issues; propose risk mitigation strategies and resolutions. \n•Leads continuous improvement efforts on existing department processes and strategies, providing recommendations in areas of expertise.\n•Supervise, mentor, and help develop the strategic and technical expertise of regulatory colleagues within the Alpine organization.\n \nQualifications:\n \n•BS/BA degree (or equivalent) in a relevant scientific field required, with an advanced degree preferred.\n•10+ years of experience in biotechnology or pharmaceutical industry with hands on experience and knowledge of the drug development process and regulatory submission and approval process required.\n•Experience working in a regulatory affairs leadership role with sole responsibility for a clinical-stage development program and marketing authorization applications, with experience as a manager/supervisor. \n•Late-stage clinical development experience and experience submitting BLAs, NDAs, and/or MAA is required.\n•CMC experience, including biologics, is desired.\n•In depth knowledge of FDA, EMA, and ICH regulatory requirements and guidelines specific to the areas of clinical research, nonclinical testing, product development, and labeling is required. \n•Must be capable of developing and implementing regulatory strategy and of managing complex negotiations with Regulatory Authorities.\n•Demonstrated ability to develop/maintain strong working relationships with cross-functional internal and external teams, participate on and/or lead multifunctional teams, manage, and prioritize multiple projects and work independently.\n•Prior global regulatory experience required; experience in Asia Pacific and Latin America is desired.\n•Strong vendor management experience is desired. \n•Therapeutic area experience in autoimmune disease is desired.\n•Must be detail-oriented while also retaining the ability to see the big picture.\n•Must have effective technical/analytical skills to identify and solve problems independently.\n•Must be able to work in a fast-paced, timeline-driven environment.\n•Should have experience writing and developing SOPs.\n\n\n\n\n\nAt Alpine we engage equitable workplace strategies to ensure fair compensation. Actual compensation is dependent upon current market data, experience, and pay parity within our organization. This is a Director level position with a compensation range of $230,000 to $270,000. Note that there is a strong preference for candidates to be located in one of the following five states: CA, MA, NC, OR, or WA. We take care of our employees with a competitive benefits package that includes stock options, annual bonus, premium medical, dental, and vision coverage for employees and their dependents, as well as life and disability benefits, FSA, and 401(k) plans. We believe quality time outside the office is vital to our employees’ satisfaction at work, so our flexible PTO plan of 160 hours, generous holiday time (generally 12 days), and parental benefits encourages team members to take time off so they can come back refreshed. Alpine team members enjoy competitive salaries and equity participation (stock options).\n\n\nAlpinists share a passion for meaningful work and are committed to solving the most complex problems in immunology to create new therapies for patients. We believe in innovative thinking, collaboration, flexibility, bias for action, and healthy debate. To foster our team of outstanding scientists and business professionals, we provide a premier work environment with a state-of-the-art lab and office spaces with truly inspiring views, and an open design to facilitate teamwork.\n\n\nOur treasured culture has been shaped by our diverse team who truly enjoys working and playing together. We nurture Alpine’s culture in many ways, including all-company social events and happy hours, lunch-and-learn and education opportunities, interest groups like book club and movie nights, peer-to-peer recognition programs, a robust wellness program to help support physical, mental, and emotional health, and more.\n\n\nAlpine is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. Alpine is also committed to compliance with all fair employment practices regarding citizenship and immigration status.\n\n\nOur office and lab are located in the blossoming biotech neighborhood of Eastlake in Seattle. Alpinists enjoy the flexibility to work onsite, remotely, or a hybrid schedule, with evolving options as we prioritize keeping Alpinists safe and healthy. Onsite employees enjoy an open-office layout with comfortable huddle rooms and Zoom Room-enabled conference rooms, a spacious breakroom and kitchen with a coffee bar and snacks, and rooftop access to enjoy gorgeous views of Lake Union and Gas Works Park.\n\n\nExciting challenges lie ahead—guided by our core values, we’ll meet these challenges.  Join us!\n  \n\n#Salary and compensation\n No salary data published by company so we estimated salary based on similar jobs related to Design, Education, Senior and Marketing jobs that are similar:\n\n $70,000 — $105,000/year\n
\n\n#Benefits\n 💰 401(k)\n\n🌎 Distributed team\n\n⏰ Async\n\n🤓 Vision insurance\n\n🦷 Dental insurance\n\n🚑 Medical insurance\n\n🏖 Unlimited vacation\n\n🏖 Paid time off\n\n📆 4 day workweek\n\n💰 401k matching\n\n🏔 Company retreats\n\n🏬 Coworking budget\n\n📚 Learning budget\n\n💪 Free gym membership\n\n🧘 Mental wellness budget\n\n🖥 Home office budget\n\n🥧 Pay in crypto\n\n🥸 Pseudonymous\n\n💰 Profit sharing\n\n💰 Equity compensation\n\n⬜️ No whiteboard interview\n\n👀 No monitoring system\n\n🚫 No politics at work\n\n🎅 We hire old (and young)\n\n
\n\n#Location\nRemote

\nAlpine Immune Sciences is a leading clinical-stage biopharmaceutical company dedicated to discovering and developing innovative, protein-based immunotherapies for autoimmune and inflammatory diseases. Exciting challenges lie ahead—guided by our core values, we’ll meet these challenges. Join us!\n\n\n\n\nAlpine Immune Sciences is seeking an energetic, passionate, and creative Senior Director/Executive Director, Corporate Communications and Investor Relations reporting to the Chief Business Officer. The successful candidate will work with senior management to develop and lead Alpine’s public relations, corporate communications, and investor relations strategy, manage the Company’s relationships with the investor community, and assist in strategic planning. The Senior Director/Executive Director, Corporate Communications and Investor Relations will align with senior management to build a strategy that communicates and elevates the Company’s mission, messaging, and key events to external stakeholders in the broader biotechnology community. The successful candidate thrives in a fast-paced, dynamic environment and will have proven experience in the design and execution of key events such as quarterly earnings calls and presentations, analyst conferences and events, road shows, press releases, social media, and other corporate activities. This is a critical and visible leadership position within the Company. As such, the successful candidate will work closely with the Chief Business Officer, Chief Financial Officer, and other executives to formulate Alpine’s overall corporate communications and investor relations strategy. \n \nDuties and responsibilities\n \n• Lead creation of corporate and financial communications, including preparation of quarterly earnings press releases and scripts, earnings presentations, Q&A, content for investor presentations, road shows, and board presentations. \n• Manage and update the Company’s corporate presentation and press releases for data releases, scientific meetings, presentations, and publications in close collaboration with Scientific Communications.\n• Manage external consulting relationships and ensure efficiency in external spending. \n• Work collaboratively to establish corporate brand planning, including brand strategy and identity, through management of company website and creation of other branding materials. \n• Oversee and lead all corporate social media activities for Company.\n• Develop a deep and thorough understanding of the Company’s pipeline and corporate strategy; support the delivery of this strategy to both internal and external audiences through clear and compelling written and oral communication, in compliance with corporate policies and securities regulations. \n• Proactively engage with buy-side and sell-side research community. \n• Lead the development and implementation of a targeted investor relations strategy to maximize the Company’s long-term value creation and ensure the consistent presentation of that strategy across all messaging.\n• Act as the liaison for Alpine’s investment banking equity research interactions to effectively leverage sell-side capabilities cross-departmentally while optimizing management time with these stakeholders.\n• Conduct periodic, in-depth, investor targeting exercises and maintain a target investor list.\n• Support financing activities, including implementation of financing strategy, managing relationships within the banking community, and executing financing activities. \n• Maintain the IR calendar, which includes strategic decisions on Company and executive participation in investor conferences, non-deal roadshows and analyst/investor meetings.\n• Ability to travel 10-25% of the time, including occasional off-hours and weekend work for events and medical meetings.\n \nQualifications\n \n• Undergraduate degree in biological sciences and/or engineering.\n• MD and/or PhD in life sciences preferred; MBA desirable.\n• 6-11 years (Senior Director), 12+ years (Executive Director), of successful experience in biotech/pharma investment banking, equity research, management consulting, biotech/pharma corporate strategy, investor relations and/or corporate communications.\n• In-depth understanding of the drug development process, small molecules, biologics, and other platforms in autoimmune and inflammatory diseases.\n• Excellent project management and organizational skills with the ability to prioritize multiple work streams and deadlines, balance opposing priorities and communicate effectively.\n• Excellent written and oral communications skills.\n• Self-starter with initiative and ability to execute once strategies are set.\n• Ability to work collaboratively with internal and external stakeholders in a fast-paced environment.\n• Knowledge of MS Office applications and especially strong in Excel and PowerPoint. \n• Experience/familiarity with social media strategy, tools, and technologies (e.g., X (Twitter), YouTube, and LinkedIn).\n\n\nLI-Remote\n\n\n\n\n\nAt Alpine we engage equitable workplace strategies to ensure fair compensation. Actual compensation is dependent upon current market data, experience, and pay parity within our organization. This position is a Senior Director level position up to an Executive Director, with a compensation range of $235,000 - $260,000 for a Senior Director, and $255,000 - $290,000 for an Executive Director. Note that there is a strong preference for candidates to be located in one of the following five states: CA, MA, NC, OR, or WA. We take care of our employees with a competitive benefits package that includes stock options, annual bonus, premium medical, dental, and vision coverage for employees and their dependents, as well as life and disability benefits, FSA, and 401(k) plans. We believe quality time outside the office is vital to our employees’ satisfaction at work, so our flexible PTO plan of 160 hours, generous holiday time (generally 12 days), and parental benefits encourages team members to take time off so they can come back refreshed. Alpine team members enjoy competitive salaries and equity participation (stock options).\n\n\nAlpinists share a passion for meaningful work and are committed to solving the most complex problems in immunology to create new therapies for patients. We believe in innovative thinking, collaboration, flexibility, bias for action, and healthy debate. To foster our team of outstanding scientists and business professionals, we provide a premier work environment with a state-of-the-art lab and office spaces with truly inspiring views, and an open design to facilitate teamwork.\n\n\nOur treasured culture has been shaped by our diverse team who truly enjoys working and playing together. We nurture Alpine’s culture in many ways, including all-company social events and happy hours, lunch-and-learn and education opportunities, interest groups like book club and movie nights, peer-to-peer recognition programs, a robust wellness program to help support physical, mental, and emotional health, and more.\n\n\nAlpine is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. Alpine is also committed to compliance with all fair employment practices regarding citizenship and immigration status.\n\n\nOur office and lab are located in the blossoming biotech neighborhood of Eastlake in Seattle. Alpinists enjoy the flexibility to work onsite, remotely, or a hybrid schedule, with evolving options as we prioritize keeping Alpinists safe and healthy. Onsite employees enjoy an open-office layout with comfortable huddle rooms and Zoom Room-enabled conference rooms, a spacious breakroom and kitchen with a coffee bar and snacks, and rooftop access to enjoy gorgeous views of Lake Union and Gas Works Park.\n\n\nExciting challenges lie ahead—guided by our core values, we’ll meet these challenges.  Join us!\n  \n\n#Salary and compensation\n No salary data published by company so we estimated salary based on similar jobs related to Design, Consulting, Education and Senior jobs that are similar:\n\n $45,000 — $85,000/year\n
\n\n#Benefits\n 💰 401(k)\n\n🌎 Distributed team\n\n⏰ Async\n\n🤓 Vision insurance\n\n🦷 Dental insurance\n\n🚑 Medical insurance\n\n🏖 Unlimited vacation\n\n🏖 Paid time off\n\n📆 4 day workweek\n\n💰 401k matching\n\n🏔 Company retreats\n\n🏬 Coworking budget\n\n📚 Learning budget\n\n💪 Free gym membership\n\n🧘 Mental wellness budget\n\n🖥 Home office budget\n\n🥧 Pay in crypto\n\n🥸 Pseudonymous\n\n💰 Profit sharing\n\n💰 Equity compensation\n\n⬜️ No whiteboard interview\n\n👀 No monitoring system\n\n🚫 No politics at work\n\n🎅 We hire old (and young)\n\n
\n\n#Location\nSeattle, WA or Remote

\nAre you ready to play a pivotal role in critical validation and development experiments and research activities to support Gordian’s path to clinical trials for novel drug candidates? \n\n\nWe’ve shown that our platform predicts preclinical and clinical physiological responses from in vivo Mosaic screens. You’ll be at the center of a fast-paced team of scientific experts using our platform to run discovery screens for more therapeutic targets than ever before, in the most realistic models of disease!\n\n\nThe Destination:\n\n\nAt Gordian Biotechnology, we are on a mission to cure age-related disease, allowing people to lead longer, healthier lives and wake up every morning, more capable than the day before. \n\n\nAge-related diseases have complex causes that include interactions with the aged environment, and traditional ex vivo screening methods have failed to produce compelling targets or effective treatments. To address this problem, Gordian’s platform enables in vivo Mosaic Screening to deliver and test hundreds of therapeutics in individual animals. We select the most clinically relevant Patient Avatars, whose age, physiology and genomics most closely resembles human patients. Using these and other proprietary tools, we can scale in vivo efficacy testing to more targets than have ever been explored by biopharma,  at the very beginning of the drug discovery process (more info on our website). This lets us develop and commercialize therapies with greater chance of impacting the world’s deadliest diseases, and eventually for the processes of aging itself. \n\n\nThe Journey:\n\n\nOur mission is audacious, and the path will be full of both challenges and excitement. Two things characterize the Gordian experience: 1) We work as a team, with ownership in our own roles and trust in each other. 2) We strive for extraordinary outcomes, and in doing so grow our skills and capability. \n\n\nTeam – Relying on each other begins with transparency. We set clear goals, visibly connecting individuals and teams to our company objectives. This empowers each of us to make autonomous decisions about our work, knowing how they will affect the bigger picture. Our communication happens out in the open. We give and receive feedback from a perspective of helping each other grow, share mistakes, and ask for help. \n\n\nExtraordinary – Every day, we ask ourselves “could this process/outcome be even better?”. Knowing our overall mission, we do what we think helps us make the most progress, without asking for permission. We don’t shy away from big challenges or unknown territory, but find a way to excel. Our colleagues are amazing, both at what they do and as people. They inspire us to keep up, to not let them down, and be inspiring in return. \n\n\nLike any cutting-edge research environment, Gordian doesn't believe in a standard 9 to 5 day. We set ambitious project goals and support each other to meet them, while maintaining the balance individuals need to thrive and achieve excellence. Our team is geared towards helping each other out, an orientation best exemplified through the support we provide for each others’ projects, both experimentally as well as through “pre-mortem” meetings to discuss possible failure modes and experimental design. We like getting things done and keep standing meetings to a minimum. \n\n\nWe like to have social as well as intellectual fun, including through weekly team lunches, monthly company happy hours, and regular social events hosted by Gordian for the broader community. We also encourage our colleagues to unwind; this year, in accordance with our unlimited vacation policy, each member took an average of 2.5 weeks of (offline) vacation, not including major holidays. \n\n\nIf this environment sounds appealing, come experience it with us. We are at the beginning of a long journey, and want both your ability and your personality along for the ride. Our culture is a source of great pride; it represents both who we are, and who we wish to be. \n\n\nYou can dive deeper here: https://www.gordian.bio/s/Gordian-values.pdf. \n\n\nThe Role:\n\n\nYour primary mission as Senior Scientist, Preclinical Development is to design and oversee experiments for validation (proof of concept) and development (IND enablement), and lead our Preclinical team’s operations to maximize scientific rigor in our drug discovery process. Specifically, you will architect experimental designs, set up new assays, disease models and gene delivery, as well as design efficacy, biodistribution and toxicity experiments to evaluate the safety and mechanism of action of potential therapeutic targets. \n\n\nYour focus at Gordian is for the validation or elimination of screen hits to happen as early as possible. Gordian is unique in that our in vivo discovery delivers results at a far greater scale than even the largest pharma company. This means that we aren’t dependent on the success of a single target, and will allow you to survey the landscape of disease biology for the most promising target (or combination of targets) before leading their development towards clinical trials. You’ll work closely with our functional teams, managing experimental schedules, and setting up in vivo systems to drive forward validation and development plans. You’ll have a significant leadership role in our Preclinical function, developing processes for your team that both minimize inefficiencies and empowers people to do their best work. \n\n\nAs an in vivo expert, you're able to provide meaningful guidance and mentorship, leading projects and providing support to your team as challenges arise.\n\n\nIn your first month you’ll become familiar with our technology and workflows, developing a strong understanding of the role of the preclinical team at Gordian, and you’ll use your expertise to quickly become familiar with our in vivo techniques. \n\n\nBy 3 months, you’ll have a strong understanding of all ongoing validation plans, and will already be thinking critically about how we can be doing them better, working closely with our team and key stakeholders to identify assays for development of each indication. You’ll contribute to the design and execution of validation experiments for two indications and will be fully onboarded to manage at least one direct report. \n\n\nBy 6 months you’ll have established efficient processes to significantly improve in vivo and assay work and will have optimized assays for four indications. You’ll be fully ramped up in your management role leading 4-5 reports on the Preclinical team. You’ll have started working closely with our disease area leads, our advisory board members and our executive team to formulate a therapeutic development plan.\n\n\nAnd You: \n\n\nYou want a chance to do your best work, immerse yourself and excel, alongside people who will inspire you and whom you’ll be excited to spend your days with. \n\n\nYou want to play a key role in an early-stage startup: A fast-paced environment full of both uncertainty and new challenges, demanding relentless resourcefulness. \n\n\nYou are excited to use cutting-edge technology to find the best therapeutic targets, and turn those into drugs. \n\n\nYou have >8 years hands-on in vivo experience (e.g. surgeries, dosing, behavior).\n\n\nYou have >4 years of industry experience in efficacy, biodistribution and toxicology studies (small molecules or biologics/gene therapies). \n\n\nYou’re an experienced people leader and have managed a team of wet lab researchers. \n\n\nYou have experience with histology and diverse assay types as well a strong data analysis skill set. \n\n\nYou have a history of managing and collaborating on time-sensitive projects, and are comfortable guiding and collaborating across multiple teams to execute experiments at a scale beyond any single person.\n\n\nExperience with pharmacokinetics/pharmacodynamics, a background designing and executing IND enablement experiments, and experience working with Lentiviruses/AAVs are all pluses. \n\n\nThe Details:\n\n\nGordian aims to provide everything you need to thrive. Beyond our community and science, you’ll have enough equity to be a true stakeholder in the company, competitive salary, full health/dental/vision/life insurance, 401k with match, onsite lunch paid for 3 days a week, an onsite gym, whatever vacation you need to be at your peak, remote work flexibility, and access to world-class mentors and advisors to support your professional growth. Our building is in the heart of the biotech capital of South San Francisco.\n\n\n\n\n$125,000 - $160,000 a year\n \n\n#Salary and compensation\n No salary data published by company so we estimated salary based on similar jobs related to Design, Testing and Senior jobs that are similar:\n\n $50,000 — $70,000/year\n
\n\n#Benefits\n 💰 401(k)\n\n🌎 Distributed team\n\n⏰ Async\n\n🤓 Vision insurance\n\n🦷 Dental insurance\n\n🚑 Medical insurance\n\n🏖 Unlimited vacation\n\n🏖 Paid time off\n\n📆 4 day workweek\n\n💰 401k matching\n\n🏔 Company retreats\n\n🏬 Coworking budget\n\n📚 Learning budget\n\n💪 Free gym membership\n\n🧘 Mental wellness budget\n\n🖥 Home office budget\n\n🥧 Pay in crypto\n\n🥸 Pseudonymous\n\n💰 Profit sharing\n\n💰 Equity compensation\n\n⬜️ No whiteboard interview\n\n👀 No monitoring system\n\n🚫 No politics at work\n\n🎅 We hire old (and young)\n\n
\n\n#Location\nSan Francisco