Dyne Therapeutics is hiring a Remote Senior Scientist Bioanalysis
\nRole Summary:\n\nThis role plays a critical role in advancing our pipeline of novel treatments through the application of cutting-edge bioanalytical techniques. This includes designing, developing, optimizing, and validating bioanalytical in complex biological matrices with a focus on muscle tissue and fluids. The person in this role is expected to utilize state-of-the-art LC-MS/MS instrumentation for the quantitative analysis of biomarkers, metabolites, and therapeutic compounds in preclinical and clinical samples.\n\nThis role is based in Waltham, MA without the possibility of being a remote role. Candidates must be able to relocate.\n\nPrimary Responsibilities Include:\n\n\n* Provide bioanalytical support for portfolio, including complex method development and troubleshooting for PK and immunogenicity assays across several programs.\n\n* Collaborate cross-functionally with Platform, Research and Non-Clinical teams.\n\n* Design, develop and/or optimize sensitive quantitative assays to measure Dyne proprietary drugs in different matrices (plasma, urine, tissues) and from different species (rodents, non-human primates, human).\n\n* Setup and maintain lab instrumentation.\n\n* Evaluate assay performance, ability to troubleshoot issues.\n\n* Perform data analysis and interpretation.\n\n* Track progress against project timelines, generate regular status updates, and communicate progress and issues to management.\n\n* Maintain a well-documented laboratory notebook.\n\n* Effectively manage workload with minimal supervision.\n\n* Adhere to safe laboratory practices.\n\n* Multi-task across several projects and manage time effectively to achieve results.\n\n* Collaborate to identify external vendors (CRO) for new outsourced projects and request contracts.\n\n* Transfer bioanalytical assays to CROs, oversee assay validation and sample testing. \n\n\n\n\nEducation and Skills Requirements:\n\n\n* BS or MS in Pharmaceutical sciences with at least 6-8 years of experience in the pharmaceutical industry or PhD degree with at least 4 years of industry experience\n\n* Broad, and in-depth knowledge of FDA bioanalytical guidance to industry\n\n* Hands-on assay development experience with different ligand binging assay formats and detection methods required\n\n* Strong assay troubleshooting, data analysis and interpretation skills\n\n* Excellent verbal and written communication skills\n\n* Ability to work collaboratively in a team-oriented environment\n\n* Strong attention to detail, organizational skills, and ability to multitask\n\n* Demonstrated ability to troubleshoot and solve problems\n\n\n\n\n \n\n#LI-Onsite \n\n#Salary and compensation\n
No salary data published by company so we estimated salary based on similar jobs related to Senior and Senior jobs that are similar:\n\n
$60,000 — $110,000/year\n
\n\n#Benefits\n
๐ฐ 401(k)\n\n๐ Distributed team\n\nโฐ Async\n\n๐ค Vision insurance\n\n๐ฆท Dental insurance\n\n๐ Medical insurance\n\n๐ Unlimited vacation\n\n๐ Paid time off\n\n๐ 4 day workweek\n\n๐ฐ 401k matching\n\n๐ Company retreats\n\n๐ฌ Coworking budget\n\n๐ Learning budget\n\n๐ช Free gym membership\n\n๐ง Mental wellness budget\n\n๐ฅ Home office budget\n\n๐ฅง Pay in crypto\n\n๐ฅธ Pseudonymous\n\n๐ฐ Profit sharing\n\n๐ฐ Equity compensation\n\nโฌ๏ธ No whiteboard interview\n\n๐ No monitoring system\n\n๐ซ No politics at work\n\n๐ We hire old (and young)\n\n
\n\n#Location\nWaltham, Massachusetts, United States
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